Drug Treatment in Schizophrenia : Issues of Comparability and Costs
نویسندگان
چکیده
Pharmacological intervention is the commonest mode of managing patients with schizophrenia. Both clinicians and patients are concerned that antipsyohotic drugs are costly and contribute to poor drug compliance in India. This study compared the equivalent doses of antipsychotic drugs and their costs across brands. Results show that antipsychotic drugs are affordable and are comparable to drug treatment costs of other physical illnesses. However, coprescription of drugs add to the burden. Numerous brands and a 2-2-1/2 fold difference in cost raises many concerns including that of drug bioavailability. Hence, the authors recommend consensus and formulation of guidelines for the pharmacological management of schizophrenia.
منابع مشابه
Investigation of DRD2 and HTR2A mRNA Expression in Two Therapeutic States of Antipsychotic Polypharmacy and Aripiprazole Monotherapy in the Peripheral Blood of Patients With Schizophrenia
Objectives: Schizophrenia is a severe psychiatric disorder that has profound effects on both individuals and the community. Notwithstanding the suggestion for treating schizophrenia with a minimum dose of drugs, antipsychotic polypharmacy increases the patient’s care costs and drug interactions. Aripiprazole reduces the metabolic side effects of antipsychotic polypharmacy treatment. DRD2 and HT...
متن کاملProtein-Protein Interaction Analysis of Common Top Genes in Obsessive-Compulsive disorder (OCD) and Schizophrenia: Towards New Drug Approach
Comorbidty is common among psychiatric disorders including obsessive-compulsive disorder and schizophrenia with a high rate. Many studies suggested that the disorders may have same etiological bases. In this regard, shared pathways of glutamate, dopaminergic, and serotonin are the known ones. Here, the common significant genes are examined to understand the possible molecular origin of the diso...
متن کاملLow Dose Celecoxib Combined with Clozapine for Treatment of Schizophrenia: A Double Blind Randomized Clinical Trial
Introduction: Higher levels of pro-inflammatory cytokines in schizophrenia have suggested that dysfunctions of the immune system may play a role in this disabling condition. The current study was performed to discover if low dose celecoxib combined with clozapine may improve symptoms of schizophrenia or not. Methods:<span...
متن کاملProtein-Protein Interaction Analysis of Common Top Genes in Obsessive-Compulsive disorder (OCD) and Schizophrenia: Towards New Drug Approach
Comorbidty is common among psychiatric disorders including obsessive-compulsive disorder and schizophrenia with a high rate. Many studies suggested that the disorders may have same etiological bases. In this regard, shared pathways of glutamate, dopaminergic, and serotonin are the known ones. Here, the common significant genes are examined to understand the possible molecular origin of the diso...
متن کاملThe effect of Ascorbic Acid as supplementary treatment with risperidone in controlling the symptoms of schizophrenia: A double-blind, placebo-controlled clinical trial
Background and Objective: Considering the hypothesis of the effects of the use of antioxidants such as ascorbic acid on the improvement of oxidative stress induced by schizophrenia, the present study was designed to investigate the effect of ascorbic acid as an adjunctive therapy with risperidone in controlling the symptoms of schizophrenia. Materials and Methods: This randomized clinical tria...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 41 شماره
صفحات -
تاریخ انتشار 1999